Knee joint replacement / Knee endoprosthetics due to degenerative diseases of the knee joint (gonarthrosis)
Initially, gonarthrosis progresses only slowly and insidiously. Nevertheless, the condition may progress rapidly, causing intense pain and significantly affecting mobility in everyday life.
The cause of the degenerative disease is usually an unbalanced mechanical stress (e.g. “bow legs” or “knock-knees”) or reduced resistance of the cartilage to inflammatory joint conditions (“rheumatism”).
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When moving the joint, the cartilage acts similarly to a sponge: When stress is applied to the joint, the synovial fluid is squeezed out of the cartilage tissue and drawn back in when the stress is removed.
Too much stress, e.g. in case of a misalignment, such as knock-knees, but also too little stress due to lack of exercise disturbs the nourishment of the bone. This insufficient nourishment reduces the resistance of the cartilage. Also inflammatory joint diseases deteriorate the composition of the synovial fluid and thus the nourishment of the cartilage as well

Although the human knee joint is capable of bearing high loads, it is also very sensitive. Due to the large bone lever of the upper and lower legs as well as the pull of the muscles, each kilogram of the body weight puts a load of approx- 3-4 kilograms onto the joint surface during walking or running. In case the power-transmitting portion of the joint surface is halved due to a congenital or acquired unbalanced stress, the pressure on the joint surface increases fourfold.
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• First symptom: fatigue after walking longer distances, yet no pain, but the wish for a break becomes more often.
• A feeling of fatigue after longer walks is often the first indication of an existing condition. There is no pain yet, but you are increasingly feeling the need to take a break.
• The progressing joint degeneration eventually causes a pulling sensation, a feeling of pressure, mild pain in the groin area, thighs or knee joints.
• In the next phase, you will experience pain while walking longer distances, walking on uneven ground or while climbing stairs.
• Pain after periods of inactivity is a typical symptom: When standing up after long sitting or when getting up in the morning, your first few steps are often painful and you always feel initial stiffness.
• At later stages, you may experience resting pain and/ or night pain.
• The more pain you experience, the more you will try to avoid painful movements. As a consequence, your muscles become tense and shorten as you adopt an unnatural posture, continuously bending your hip and causing the joint capsule and ligaments to shrink. Ultimately, the range of motion of your hip joint decreases and movement becomes painful.
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• Lateral x-ray image of the knee joint
• Initially, the joint cartilage is worn down. This cartilage is not directly visible in X-ray images, but it can be seen as a dark seam between the bright osseous joint parts, referred to as joint space (= permeable to X-rays). Representing the extent of cartilage damage, this joint space becomes increasingly smaller, until the two bones are ultimately touching each other.
• With increasing joint stress, the bone tissue also responds by thickening in the areas of overloading. X-ray images then show sclerosis (thickening) as a bright band (= impermeable to X-rays). The under-loaded part of the bone rather appears to be more transparent than usual.
• Osteophytes (bone spurs) increasingly occur on the joint’s surface area.
• In the areas of overloading, a loss of blood supply arises, the bone tissue dies and small cysts (cavities) form. They frequently appear in pairs opposite to each other on neighbouring bone parts.
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The first step is anamnesis, i.e. a systematic analysis of your case history. In this process, your current state of health, your living environment (e.g. occupational stress), your case history (e.g. internal-medical diseases), particular risk factors (e.g. allergies) as well as genetic (hereditary) risks are evaluated. The following questions are typical:
What are the symptoms, when did they start and how often do they appear?
What seems to cause the symptoms (physical exertion, sports)? Howe can they be alleviated?
Have you tried-self treatment (home remedies) and what did your physician prescribe (medication, physical therapy)?
Do you have any other conditions?
What medication do you take regularly?
weiter zu Examination...
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During the thorough physical examination we ascertain and evaluate joint swellings, mobility, stability, pressure and pain during movement of the affected joint and the neighbouring joints, in addition to posture, misalignment of limbs and spine, nervous disorders, blood supply, height and weight.
The results usually yield a first diagnosis, which will then be confirmed, if necessary, using additional imaging techniques, and/or distinguished from similar signs and symptoms.
weiter zu X-ray...
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For basic diagnostics, usually three x-ray images are taken: one in front view, a side image and one of the patella in its sheath.
In case an axis measurement is required, the whole leg including the hip and ankle joints is displayed.
weiter zu CT/MRI...
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Magnetic resonance imaging
Magnetic Resonance Imaging (MRI or nuclear spin tomography; cross-sectional image using magnetic fields) measures the content of hydrogen atoms in different tissues, instead of working with x-rays. This imaging technique shows both bones and soft tissue such as cartilage, ligaments, muscles and tendons. At early and intermediate stages of a degenerative disease, it can be very helpful to accurately determine the extent of cartilage damage
Computer tomography
In some particular cases, computed tomography (CT, cross-sectional imaging technique using x-rays) is employed to complement conventional X-ray visualisation. CT generates a three-dimensional image of the hip joint, so that the joint can be precisely measured and, most importantly, misalignments can be determined.
Sonography
Sonography (ultrasound examination) of the knee joint is of secondary importance in the diagnostics of gonarthrosis. However, it allows for visualising the concomitant alterations of soft tissues, which cannot be seen in the x-ray image.
weiter zur Prophylaxe...
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In case of pre-damaged knees, it is reasonable to use moving stairs or lifts. Exercising is certainly important but not on stairs!
The following preventive measures can help you to actively counteract the development of the disease or slow down its progression at an early stage.
Is your work mostly sedentary?
• Move your legs repeatedly!
• Stand up as often as possible and walk a few steps!
Do physical exercise!
• Cycling, swimming, Nordic walking and cross-country skiing are particularly suitable.
• Try to avoid stop-and-go sports such as tennis, table tennis, squash and badminton as well as most team sports such as handball, football, volleyball, etc.
Move your joints to their full extent!
• Do gymnastics on a regular basis!
• Exercise and stretch your muscles!
• Stretch shortened joint capsules and ligaments!
If you have a pre-existing condition, try to avoid heavy lifting!
• Every extra pound on your body puts additional pressure on your hip joint!
• Use a shopping cart rather than a shopping bag!
• When you are carrying loads, use an escalator or elevator.
• Take the load off your joints by using a walking stick!
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Our treatment methods are always tailored to the individual patient and his particular case history – You will see that with our specialists you are in the right hands.
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> Joint injections: mehr...
Physiotherapy:
Individualised physical therapy is combined with easy-to-understand instructions for self-treatment, to alleviate your discomfort, stabilise your cartilage and strengthen your muscles, helping you to significantly improve your mobility.
Balneotherapy (heat and cold) and physical therapy
Application of heat and cold; ultrasound and electrotherapy supplement the treatment. They effect the enhancement of blood circulation and thus an improvement of the joint nourishment.
(For the rest, see coxarthrosis)
Antiphlogistics (anti-inflammatory medication):
Anti-inflammatory therapies, also referred to as antiphlogistics, are our first choice for all medical conditions of the musculoskeletal system. In addition to their anti-swelling and anti-inflammatory effect, their active ingredients also relieve pain in different strengths. The side effects of these medications particularly affect the stomach and kidneys (e.g. Ibuprofen, Diclofenac, Indometacin).
Cartilage-building supplements:
Gelatines, Chondroitin sulfate and glucosamine sulfate are supplements with scientifically proven efficacy. However, treatment over a period of six to twelve weeks is necessary to achieve the desired effect.
Pure analgesics (pain medication):
Pure analgesics do no treat the cause of arthrosis. Although they relieve pain, they have no effect on the inflammatory processes in the body (examples: (e.g. Paracetamol, Metamizol, Tramadol).
Hyaluronic acid is a normal building block of healthy joint cartilage. The molecule is created in the lab to be injected into the joint, where it is integrated into the cartilage. The hyaluronic acid stabilises the cartilage, smoothes the unevenness on its damaged surface and improves the lubricating properties of the synovial fluid.
Cortisone is the best anti-inflammatory medication known today. Typical side effects (e.g. high blood pressure) primarily occur when taken as a pill or injected intravenously. Only in very rare cases do these side effects occur when cortisone is injected into a joint.
Arthroscopy: Joint endoscopy
During arthroscopy, nearly all damages in the interior of the knee joint can be treated by means of an optical system with the diameter of a pencil and small instruments, which are usually inserted into the joint via two incisions of 0.5 cm in size.
Destroyed meniscus tissue and the instability of the joint enhance the development of the arthrosis. For this reason, destroyed meniscus tissue is removed or, under certain circumstances, also sutured; torn cruciate ligaments are usually replaced by endogenic tendon tissue (cruciate ligament reconstruction). The surface of already degenerated cartilage is smoothened. Deep cartilage defects can be covered by cultivating fibrous cartilage or by cartilage transplantation.
Displacement osteotomy: Correction of misalignments
The displacement osteotomy corrects rotational misalignments, i.e. “bow legs” or “knock-knees”. As a result, the previously overstressed inner or outer joint portion is relieved.
The correction is performed by either removing a bone wedge or spreading apart and filling the bone gap with bone tissue from the iliac crest. The surgery can be performed near the joint on the upper leg, the lower leg or, in rare cases, also on both bones simultaneously. The bone surfaces are attached to each other by means of clips or metal plates and screws.
Until the bone has fully healed after approx. twelve weeks, the joint will have moving stability, but only limited weight-bearing stability. Therefore, the patient will have to rely on crutches for the rehabilitation period of twelve weeks. This surgery is recommended in cases where an endoprosthesis can still be delayed by 5 years or, ideally, 10 years.
The knee joint has a complex structure; it is much more complicated to imitate its movement than e.g. that of the hip joint. For this reason, much more development work was required until well-functioning knee endoprostheses were available. Today mature products of various manufacturers are available.

The shape of the endoprosthesis and the surgery technique during its implantation are dependent upon the location and the extent of the cartilage damage, the degree of the rotational misalignment and the stability of the capsule-ligament apparatus.
Anchoring in the bone
The prosthesis can be anchored in the bone with or without osteocementum.
A cement-free endoprosthesis first wedges in the bone, which subsequently grows onto its rough surface. Cemented endoprostheses are anchored (“cemented”) in the bone by means of a plastic material similar to acryl glass.
According to the current state of knowledge, there is no difference between the two anchoring types of artificial knee joints with respect to the service life of the implant. We use both methods, however, more often the cemented version, as the acrylic cement does not compensate the unevenness in the bone and a cement-free knee endoprosthesis may not grow into the bone optimally.
> Bicondylar (bilateral) sledge prosthesis – the standard implant mehr...
> Fully constrained prostheses – the coupling mehr...

Unicondylar sledge prosthesis
This “small” knee endoprosthesis is the appropriate implant in cases where the arthrosis is limited to the inner side and the cartilage between the patella and its sheath on the upper leg is intact. Furthermore, the leg axis and the knee ligaments have to be stable. These prerequisites are usually only fulfilled after an accident or in case of Ahlbäck’s disease (localised circulatory disorder at the medial condyle).
During surgery, the destroyed cartilage is removed together with a thin bone layer and replaced by the implant. The destroyed cartilage can be replaced by a plastic knob on the back surface of the patella as well. The artificial joint is held in place by the natural capsule-ligament apparatus. Only the front cruciate ligament needs to be removed. The prerequisite for a perfect movement is the correction of the defective leg axis and the balancing of slack collateral ligaments.

An improvement of the bicondylar sledge prosthesis are the so-called “modular implant systems”. These systems allow for attaching shafts to the upper and lower leg components as well as for underlaying the bone contact areas with metal components after accidents or during revision surgeries.
All high-quality, modern implants provide you long-term alleviation of your pain and unlimited mobility in your everyday life - we recommend the most suitable option for your individual needs.
Above all in case of extensive axis defects, the conventional surgery technique involves certain error sources. Due to the computer-aided surgery using a navigation system, however, these can be minimised - this provides the patient with maximum safety. Just like the navigation system of a car, giving instructions to the driver but not steering itself, the navigation system provides the surgeon information about the position of the surgical instruments, the position of the leg axis and the stability of the ligament apparatus. However, the surgery still takes place manually on the basis of this information.
At the beginning of the surgery, markers are fixed on the upper and lower legs and the accurate data of the knee joint entered into the system by means of a measuring probe. The computer calculates a three-dimensional model out of this data. By means of its camera, the navigation system is then capable of visualising the position of the bones and the surgical instruments with the highest degree of precision. The surgeon is able to accurately position his instruments using the navigation system and check the accuracy of the performed incisions in a further step. The strain of the capsule-ligament apparatus is measured and balanced out by means of the computer system. The result of the surgery can be measured and, if necessary, also corrected already during the surgery.
A straight leg axis and higher degree of mobility provides the patient a better functionality of the artificial joint but above all the best prerequisite for a long service life of the endoprosthesis.
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Rehabilitation up to complete recovery
The goal is the patient’s complete recovery after surgery within the shortest possible period of time. Therefore, we select an as mild as possible surgery technique for each patient individually.
The patient is usually able to start with the physical therapy as early as on the date of the surgery. In case of normal recovery course as well as good health constitution, full weight may be placed upon the joint again after a few days and the patient is only dependent on two walking crutches only for about 6 weeks.
In order to ensure full recovery, we recommend that you undergo inpatient or outpatient rehabilitation after your stay at the hospital. We will be happy to assist you in choosing a facility and we will also take care of all the formalities with your insurance company.
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