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Degenerative diseases of the hip joint (coxarthrosis, arthrosis)



Coxarthrosis (a degenerative disease of the hip joint, coxa = hip, arthros = joint) is a very common condition in adults. Hip joint degeneration starts with the destruction of joint cartilage (the hard, elastic and smooth coating of bones in the area of joint surfaces). As the condition progresses, soft tissues (e.g. joint capsule, ligaments) and the bone may also become affected.

Initially, symptoms of coxarthrosis are often not very noticeable. Nevertheless, the condition may progress rapidly, causing intense pain and significantly affecting mobility in everyday life.

A degenerative disease is often caused by excessive mechanical stress or reduced resistance of the cartilage to inflammatory joint conditions. 

 
Fortgeschrittene Arthrose im Hüftgelenk
Advances osteoarthritis of the hip

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Insufficient joint nourishment

Cartilage tissue does not have any nourishing blood vessels, but is supplied by synovial fluid. When stress is applied to the joint, the synovial fluid is squeezed out of the cartilage tissue – similar to a sponge – and drawn back in when the stress is removed.

However, when too much stress is applied to cartilage tissue, for example in the form of excessive pressure forces, its smooth surface is mechanically destroyed. The cartilage becomes frayed and is progressively depleted. In most cases, this stress overload is due to misalignment between the head of the femur and the acetabulum. This misalignment may either be congenital or acquired as a consequence of a disease or an accident.


Knorpelveränderung bei
einer Fehlbelastung




The most common causes are:

• Hip dysplasia (congenital deformation), in some cases including luxation (dislocation)
• Epiphysiolysis (separation of the growth plate during puberty)
• Femur head necrosis (loss of blood supply causing death of bone tissue)
• Accidents


Too little mechanical stress may also disrupt the nourishment of the cartilage. Inflammatory joint diseases (rheumatism) deteriorate the composition of synovial fluid. Overweight, hard physical labour and repetitive strain are never the cause of the condition, but these factors accelerate its progression.

Angeborene hohe Hüftluxation
Congenital hip dislocation high

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The symptoms listed below should make you consider your daily physical activities, to see if preventative measures need to be taken or if treatment may be necessary.

• A feeling of fatigue after longer walks is often the first indication of an existing condition. There is no pain yet, but you are increasingly feeling the need to take a break.
• The progressing joint degeneration eventually causes a pulling sensation, a feeling of pressure, mild pain in the groin area, thighs or knee joints.
• In the next phase, you will experience pain while walking longer distances, walking on uneven ground or while climbing stairs.
• Pain after periods of inactivity is a typical symptom: When standing up after long sitting or when getting up in the morning, your first few steps are often painful and you always feel initial stiffness.
• At later stages, you may experience resting pain and/ or night pain.
• The more pain you experience, the more you will try to avoid painful movements. As a consequence, your muscles become tense and shorten as you adopt an unnatural posture, continuously bending your hip and causing the joint capsule and ligaments to shrink. Ultimately, the range of motion of your hip joint decreases and movement becomes painful.


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As coxarthrosis progresses, the changes in the hip joint also become visible in X-ray images.

• Initially, the joint cartilage is worn down. This cartilage is not directly visible in X-ray images, but it can be seen as a dark seam between the bright osseous joint parts, referred to as joint space (= permeable to X-rays). Representing the extent of cartilage damage, this joint space becomes increasingly smaller, until the two bones are ultimately touching each other.
• With increasing joint stress, the bone tissue also responds by thickening in the areas of overloading. X-ray images then show sclerosis (thickening) as a bright band (= impermeable to X-rays). The under-loaded part of the bone rather appears to be more transparent than usual.
• Osteophytes (bone spurs) increasingly occur on the joint’s surface area.
• In the areas of overloading, a loss of blood supply arises, the bone tissue dies and small cysts (cavities) form. They frequently appear in pairs opposite to each other on neighbouring bone parts. 

 

Fortgeschrittene starke Arthrose

Advanced osteoarthritis strong


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Anamnesis – comprehensive and thorough

The first step is anamnesis, i.e. the systematic analysis of your medical history. In this process, your current state of health, your living environment, your case history (e.g. organic diseases), particular risk factors as well as genetic (hereditary) risks are evaluated. The following questions are typical:

• What are the symptoms, when did they start and how often do they appear?
• What seems to cause the symptoms (physical exertion, sports)? How can they be alleviated?
• Have you tried self-treatment (home remedies)?
• What did your physician prescribe (medication, physical therapy)?
• Do you have any other conditions, including non-orthopaedic ones?
• What medication do you take regularly?

This is followed by thorough physical examination, in which we ascertain joint swellings, mobility, stability, pressure and pain during movement of the affected joint and the neighbouring joints, in addition to height, weight, posture, misalignment of limbs and spine, nervous disorders and blood supply. The results usually yield a first diagnosis, which will then be confirmed, if necessary, using additional imaging techniques, and/or distinguished from similar signs and symptoms.


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For basic diagnostics, usually two X-ray images are taken, to provide a front view as well as a side view of the hip joint at an inclined angle.

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Magnetic Resonance Imaging
Magnetic Resonance Imaging (MRI or nuclear spin tomography; cross-sectional image without X-rays) measures the content of hydrogen atoms in different tissues. This imaging technique shows both bones and soft tissue (cartilage, ligaments, muscles and tendons). At early and intermediate stages of a degenerative disease, it can be very helpful to accurately determine the extent of cartilage damage.

Computed tomography
In some particular cases, computed tomography (CT, cross-sectional imaging technique using x-rays) is employed to complement conventional X-ray visualisation. CT generates a three-dimensional image of the hip joint, so that the joint can be precisely measured and, most importantly, misalignments can be determined.

Sonography
Sonography (ultrasound examination) of the hip joint is of secondary importance in the diagnostics of coxarthrosis. Nevertheless, this procedure allows for the evaluation of accompanying joint effusions, which cannot be directly seen in X-ray images. In infants, however, ultrasound can be used shortly after birth to determine whether hip dysplasia or dislocation is present, so that treatment can be initiated in time.

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Although cartilage is nourished through the motion of the joint, excessive stress should be avoided. Joints need to be moved frequently, so that their cartilage is well nourished and they possess the strength to withstand additional short-term stress without injury. Activities that place excessive stress on the joints, such as heavy lifting and carrying should be avoided in everyday life as far as possible.

The following preventive measures can help you to actively counteract the development of the disease or slow down its progression at an early stage.

Is your work mostly sedentary?
• Move your legs repeatedly!
• Stand up as often as possible and walk a few steps!

Do physical exercise!
• Cycling, swimming, Nordic walking and cross-country skiing are particularly suitable.
• Try to avoid stop-and-go sports such as tennis, table tennis, squash and badminton as well as most team sports such as handball, football, volleyball, etc.

Move your joints to their full extent!
• Do gymnastics on a regular basis!
• Exercise and stretch your muscles!
• Stretch shortened joint capsules and ligaments!

If you have a pre-existing condition, try to avoid heavy lifting!
• Every extra pound on your body puts additional pressure on your hip joint!
• Use a shopping cart rather than a shopping bag!
• When you are carrying loads, use an escalator or elevator.
• Take the load off your joints by using a walking stick!

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Our treatment methods are always tailored to the individual patient and his particular case history – You will see that with our specialists you are in the right hands.


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> Medication treatment mehr...
> Joint injections mehr...

Physiotherapy:
Individualised physical therapy is combined with easy-to-understand instructions for self-treatment, to alleviate your discomfort, stabilise your cartilage and strengthen your muscles, helping you to significantly improve your mobility.

Additional Physical Therapy:
The usage of heat, cold, ultrasound or electrotherapy complements the treatment. These techniques promote blood flow and thus improve joint nourishment.



Antiphlogistics (anti-inflammatory medication):
Anti-inflammatory therapies, also referred to as antiphlogistics, are our first choice for all medical conditions of the musculoskeletal system. In addition to their anti-swelling and anti-inflammatory effect, their active ingredients also relieve pain in different strengths. The side effects of these medications particularly affect the stomach and kidneys (e.g. Ibuprofen, Diclofenac, Indometacin).

Cartilage-building supplements:
Gelatines, Chondroitin sulfate and glucosamine sulfate are supplements with scientifically proven efficacy. However, treatment over a period of six to twelve weeks is necessary to achieve the desired effect.

Pure analgesics (pain medication):
Pure analgesics do no treat the cause of arthrosis. Although they relieve pain, they have no effect on the inflammatory processes in the body (examples: (e.g. Paracetamol, Metamizol, Tramadol).



Hyaluronic acid:
Hyaluronic acid is a normal building block of healthy joint cartilage. The molecule is created in the lab to be injected into the joint, where it is integrated into the cartilage. The hyaluronic acid stabilises the cartilage, smoothes the unevenness on its damaged surface and improves the lubricating properties of the synovial fluid. 
 
S14_02_Knorpelaufbau
Cluster of hyaluronic acid molecules embedded in cartilage tissue and settled on its surface
Cortisone:
Cortisone is the best anti-inflammatory medication known today. Typical side effects (e.g. high blood pressure) primarily occur when taken as a pill or injected intravenously. Only in very rare cases do these side effects occur when cortisone is injected into a joint.


The goal of our treatment is always to preserve your natural hip joint for as long as reasonably possible, and only replace it by an endoprosthesis (artificial implant, Greek endo= inside the body, prosthesis = artificial) when there is no other option. If you have coxarthrosis, however, you should not wait “until the last minute“, but rather see us for a consultation in time. There may still be the possibility of preservation treatment.

In any case, the correction of misalignments is a prerequisite for the long-term success of any preservation procedure, because in conditions where the original, healthy cartilage was overloaded, new cartilage will not be able to survive, either.


Osteotomy procedures: correction of misalignments

Congenital and acquired deformities can be corrected more easily at an early stage, i.e. during childhood. In young adults suffering from hip pain, VDRO = varus-derotational osteotomy (three-dimensional realignment surgery of the femur) and/or pelvic surgery may be necessary. Improved alignment and weight distribution in the hip joint helps slow down joint degeneration. Of course, such a surgical procedure needs to be carefully planned. Stabilisation is achieved using special plates and screws.

Until the bone has fully healed after approx. twelve weeks, the joint will have moving stability, but only limited weight-bearing stability. Therefore, the patient will have to rely on crutches for the rehabilitation period of twelve weeks. This surgery is performed in cases where an endoprosthesis can still be delayed by 5 years or, ideally, 10 years.



In Germany, approx. 200,000 artificial hip joints are implanted annually. Endoprostheses, surgical instruments and minimally invasive surgery techniques (= surgery where only a very small portion of surrounding tissue is injured) are continuously enhanced, thereby extending the service life of artificial joints considerably. As a result, artificial joints have now also become an option for younger and physically active patients. Today, a well-implanted total hip replacement lasts about 15 years and enables you to lead a pain-free life. One or even several revision surgeries are possible.


When is the right time for hip replacement?

Your pain is becoming more severe, even when resting and at night. The mobility of your hip joint is deteriorating and your pain-free walking distances are becoming shorter. Previous treatment measures no longer help and your quality-of-life is significantly affected. In this case, you should consult your physician or directly talk to us.



For the implantation of a cement-free standard endoprosthesis, the acetabulum and the femoral head are removed, and the diseased cartilage is drilled out of the joint socket of the pelvis. The shaft of the endoprosthesis is then pressed into the body of the femur and firmly wedged in the bone. The acetabular cup is either also pressed in or screwed in. Subsequently, the bone grows towards the implant and integrates with its surface (osseointegration).

Zementfrei implantierbarer Titan-Schaf
Cementless implantable titanium shaft

Since bone tissue is constantly being remodelled at any age, we always prefer to anchor the implant without the use of cement whenever possible. In order to achieve this, manufacturers offer implants in a very wide range of shapes, sizes and surface structures. It is understood that cementless implants last longer than cemented ones, which are anchored in the shaft of the femur or the pelvic bone using a plastic material.

Zementfreie
Press-Fit Pfanne
Cementless press-fit cup

If an implant is not immediately tight and stable after surgery, it will not be in the future, either. For this reason, sufficient bone density is critical for the use of a cementless implant. An advanced case of osteoporosis is a clear contraindication for cementless implants.


In cases of poor bone density, for example due to osteoporosis, cementless implants cannot be anchored with sufficient stability. Cemented implants, however, are anchored in the bone using bone cement (a plastic material similar to acrylic glass). Following a short hardening period, the implant already has full weight-bearing capacity during surgery.

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left: Advanced coxarthrosis, osteoporosis
right: Cemented hip prosthesis 
 


Hybrid prostheses are a mixture of a cup anchored without the use of cement and a cemented implant shaft. This combination is useful in cases where good bone quality of the pelvis stands in contrast to osteoporotic, soft bone tissue of the femur.

links: Schenkelhalsbruch bei
Osteoporose, rechts: Zementfreie Schraubpfanne
mit zementiertem Schaft
left: Femoral neck fracture due to osteoporosis,
right: Cementless screw-cup with cemented shaft


The cap implant is the smallest endoprosthesis, and therefore the one where the least amount of bone needs to be removed. The damaged cartilage is removed from the head of the femur and a metal cap similar to a dental crown is attached the head of the femur. Its counterpart is a metal cup, which is inserted without the use of cement into the acetabulum after the cartilage has been removed.

Its advantages include very little friction between the two metal parts, excellent manoeuvrability and a very large head of the implant, which significantly reduces the risk of hip dislocation. Therefore, this implant is particularly suitable for physically active and often younger patients. However, good bone density is a prerequisite, because otherwise there is the risk of femoral neck fracture. One disadvantage is that, despite minimal friction, metal ions are released which may become enriched in the bodies of patients with hepatic or renal disorders.



In order to implant a standard endoprosthesis, the damaged head of the femur is removed together with the femoral neck, i.e. healthy bone tissue. For a short-shaft endoprosthesis, only the head of the femur needs to be removed, and the implant is anchored in the remaining femoral neck without the use of cement. The implant is smaller and more bone is preserved. Therefore, this represents a suitable alternative to a standard implant, especially for younger and physically active patients, who may require several replacement revision surgeries in the course of their lives. However, there are no reports on long-term results available yet. Osteoporosis is a clear contraindication for this procedure, as is the case with any other cementless implant type.



For atypical bone shapes (e.g. after previous surgeries or in patients with spasticity – an abnormal increase in muscle tension), standard endoprostheses are often not suitably shaped. A modular implant is composed of several building blocks, so that different individual components can be combined to form an implant that is tailored to the respective bone structure. This allows for stable and cementless anchoring even in cases of pronounced deformities.


left: Female patient with spasticity, high hip dislocation and several previous surgeries
right: Modular implant in shortened femoral bone 
 


Artificial hip replacements consist of a metal cup into which an additional inlay of polyethylene, metal or ceramic is inserted to serve as a sliding bearing. This cup accommodates the artificial femoral head of metal or ceramic. Currently, the most commonly used inlay material is high-density polyethylene, similar to the material used for ski coating. Although good long-term results have been reported, we know that approx. 80% of all cases of implant loosening that were not caused by infection are due to abrasion of polyethylene particles (particle disease). For this reason, we use a considerably more expensive combination of ceramic inlays and ceramic heads whenever possible. It sheds 200 times less particles, which are not harmful to bone health, and is therefore far more likely to last longer.

High-precision head and cup inlays are available in different sizes. If possible, we use large-sized heads with a diameter of 36 mm (standard: 28 mm and 32 mm) In doing so, a greater ranger of motion is achieved and the risk of dislocating the artificial joint is reduced.

v.l.n.r.: Keramik-Keramik-Gleitpaarung, Inlay und Hüftkopf, Hüftoberflächenersatz, Modulare Endoprothese
from left to right.: ceramic-ceramic-sliding pair, inlay and femoral head,
hip surface replacement, modular endoprosthesis


Rehabilitation begins as early as on the date of the surgery, and the next day you will already be taking your first few steps with your new hip joint. Step by step, its load-bearing capacity will increase. During this process, you will also learn to follow the restrictions that total hip replacement entails. For example, you should avoid low sitting positions and crossing your legs during the first three months to eliminate the risk of dislocation.

Under normal recovery circumstances, you should use two forearm crutches for about six weeks after surgery, although you will already be able to place full weight on the joint much earlier. The crutches will help you to avoid limping and regain a normal walking gait.

In order to ensure full recovery, we recommend that you undergo inpatient or outpatient rehabilitation after your stay at the hospital. We will be happy to assist you in choosing a facility and we will also take care of all the formalities with your insurance company.

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